ʻO Desmopressin Acetate e mālama i ka maʻi diabetes Insipidus
Huahana Huahana
| inoa | Desmopressin |
| Helu CAS | 16679-58-6 |
| ʻAno molekala | C46H64N14O12S2 |
| Kaumaha molekula | 1069.22 |
| Helu EINECS | 240-726-7 |
| Kahuli kiko'ī | D25 +85.5 ± 2° (helu ʻia no ka peptide manuahi) |
| ʻO ka mānoanoa | 1.56±0.1 g/cm3 (Wānana ʻia) |
| RTECS No. | YW9000000 |
| Nā kūlana mālama | E mālama i ka 0°C |
| Ka hoʻoheheʻe | H2O:soluble20mg/mL, akaka, kala ole |
| ʻO ka ʻakika coefficient | (pKa) 9.90±0.15 (Wanamua) |
Nā huaʻōlelo like
MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2; MINIRIN; [DEAMINO1, DARG8] VASOPRESSIN; [DEAMINO-CYS1, D-ARG8]-VASOPRESSIN; DDAVP, KANAKA; DESMOPRESSIN; DESMOPRESSIN, KANAKA; DESAMINO-[D-ARG8] VASOPRESSIN
Nā hōʻailona
(1) Ka mālama ʻana i ka maʻi diabetes insipidus waena. Ma hope o ka lāʻau lapaʻau hiki ke hōʻemi i ka urinary excretion, hoʻemi i ka pinepine urinary a hoʻemi i ka nocturia.
(2) Hoʻomaʻamaʻa i ka enuresis nocturnal (nā maʻi he 5 makahiki a ʻoi paha).
(3) E ho'āʻo i ka hana o ka mimi renal, a e hoʻokō i ka hōʻailona ʻokoʻa o ka hana renal.
(4) No ka hemophilia a me nā maʻi koko ʻē aʻe, hiki i kēia huahana ke hoʻopōkole i ka manawa koko a pale i ke koko. Hiki iā ia ke hoʻemi i ka nui o ke kahe koko intraoperative a me ka oozing postoperative; ʻoi aku i ka hui pū ʻana me ke kahe koko i hoʻopaʻa pono ʻia i ka wā o ka ʻoki ʻana, hiki iā ia ke hōʻemi i ke koko intraoperative mai nā ʻano hana like ʻole, a hoʻemi i ka oozing postoperative, hiki ke pāʻani i kahi ʻoi aku ka maikaʻi o ka pale koko.
Ka mālama ʻana i ka maʻi diabetes insipidus
ʻO ka maʻi diabetes insipidus ka maʻi maʻamau o ka metabolism wai i hōʻike ʻia e ka nui o ka mimi, polydipsia, hypoosmolarity, a me hypernatremia. Hiki ke hoʻomaka ka hapa a i ʻole ka hapa piha o ka vasopressin (central diabetes insipidus), a i ʻole ka lawa ʻole o ka renal o vasopressin (nephrogenic diabetes insipidus). ʻO ka maʻi maʻi, ua like ka maʻi diabetes insipidus me ka polydipsia mua, kahi maʻi i loaʻa ai ka nui o ka inu wai ma muli o ka hana ʻole o ka mīkini hoʻoponopono a i ʻole ka makewai ʻano ʻole. Kūlike ʻole i ka polydipsia mua, ʻo ka hoʻonui ʻana i ka inu wai i nā poʻe maʻi me ka maʻi diabetes insipidus he pane kūpono ia i nā loli o ka osmotic pressure a i ʻole ka nui o ke koko.
