Eptifibatide no ka mālama ʻana i ka maʻi maʻi maʻi maʻi 188627-80-7
Huahana Huahana
| Inoa | Eptifibatide |
| Helu CAS | 188627-80-7 |
| ʻAno molekala | C35H49N11O9S2 |
| Kaumaha molekula | 831.96 |
| Helu EINECS | 641-366-7 |
| ʻO ka mānoanoa | 1.60±0.1 g/cm3 (Wānana ʻia) |
| Nā kūlana mālama | Hoʻopaʻa ʻia i kahi maloʻo, mālama i loko o ka pahu hau, ma lalo o -15 ° C |
Nā huaʻōlelo like
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6- (Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2 (DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein Antagonist
ʻO Etifibatide (integrilin) he mea hou polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, ka mea e pale ai i ka platelet aggregation a me ka thrombosis ma ke kāohi ʻana i ke ala maʻamau hope o ka platelet aggregation.Hoʻohālikelike ʻia me ka monoclonal antibody abciximab, ʻoi aku ka ikaika o ka eptifibatide, ʻoi aku ka kuhikuhi a me ka paʻa kikoʻī iā GPIIb/IIIa ma muli o ka noho ʻana o kahi hoʻololi amino acid conservative-lysine e pani i ka arginine.No laila, pono e loaʻa kahi hopena therapeutic maikaʻi i ka mālama interventional o ka maʻi coronary acute.ʻO ka platelet glycoprotein IIb/IIIa receptor antagonist lāʻau i hoʻomohala nui ʻia, a i kēia manawa aia he 3 mau ʻano hoʻomākaukau i hiki ke hoʻohana ʻia i ka lāʻau lapaʻau honua, abciximab, eptifibatide a me tirofiban.).ʻAʻohe ʻike liʻiliʻi i ka hoʻohana ʻana i ka platelet glycoprotein GPIIb/IIIa receptor antagonists ma Kina, a ʻo nā lāʻau lapaʻau i loaʻa i kaupalena ʻia.Hoʻokahi wale nō lāʻau, ʻo tirofiban hydrochloride, aia ma ka mākeke.No laila, ua kūkulu ʻia kahi platelet glycoprotein IIb hou./IIIa receptor antagonists imperative.ʻO ka eptifibatide home kahi huahana hoʻohālike i hana ʻia e Chengdu Sino Biological Products Co., Ltd.
Hoʻokaʻawale
Hoʻokaʻawale i nā lāʻau antiplatelet Aggregation
Hiki ke hoʻokaʻawale ʻia nā lāʻau antiplatelet aggregation i ʻekolu mau ʻāpana: 1. Cyclooxygenase-1 (COX-1) inhibitors, e like me ka aspirin.2. Kāohi i ka platelet aggregation i hoʻokomoʻia e ka adenosine diphosphate (ADP), e like me clopidogrel, prasugrel, cangrelor, ticagrelor, a me nā mea'ē aʻe. prostaglandin EP3 receptor inhibitors, mea hou synthesized kemika a me nā unuhi kūpono mai ka lāʻau lapaʻau Kina.
