Semaglutide no ka maʻi maʻi type 2
Huahana Huahana
| Inoa | Semaglutide |
| Helu CAS | 910463-68-2 |
| ʻAno molekala | C187H291N45O59 |
| Kaumaha molekula | 4113.57754 |
| Helu EINECS | 203-405-2 |
Nā huaʻōlelo like
Sermaglutide;Semaglutide fandachem;Semaglutide haumia;Sermaglutide USP/EP;semaglutide;Sermaglutide CAS 910463 68 2;Ozempic,
wehewehe
ʻO Semaglutide kahi hanauna hou o GLP-1 (glucagon-like peptide-1) analogues, a ʻo ka semaglutide kahi ʻano hana lōʻihi i hoʻomohala ʻia ma muli o ke ʻano kumu o ka liraglutide, ʻoi aku ka maikaʻi o ka mālama ʻana i ka maʻi diabetes type 2.Ua hoʻopau ʻo Novo Nordisk i nā haʻawina 6 Phase IIIa o ka semaglutide injection, a ua hāʻawi i kahi palapala hoʻopaʻa inoa lāʻau hou no ka semaglutide i kēlā me kēia pule i ka US Food and Drug Administration (FDA) ma Dekemaba 5, 2016. Ua waiho pū ʻia kahi Palapala Hoʻolaha Kūʻai (MAA) i ka. ka European Medicines Agency (EMA).
Hoʻohālikelike ʻia me ka liraglutide, he kaulahao aliphatic lōʻihi ka semaglutide a hoʻonui i ka hydrophobicity, akā hoʻololi ʻia ka semaglutide me kahi kaulahao pōkole o PEG, a ua hoʻonui nui ʻia kona hydrophilicity.Ma hope o ka hoʻololi ʻana o ka PEG, ʻaʻole hiki iā ia ke hoʻopaʻa i ka albumin wale nō, e uhi i ka pūnaewele hydrolysis enzymatic o DPP-4, akā e hōʻemi hoʻi i ka renal excretion, e hoʻolōʻihi i ka hapalua ola, a loaʻa i ka hopena o ka holo lōʻihi.
Palapala noi
ʻO Semaglutide kahi ʻano hana lōʻihi i hoʻomohala ʻia ma muli o ke ʻano kumu o ka liraglutide, ʻoi aku ka maikaʻi o ka mālama ʻana i ka maʻi diabetes type 2.
Mea olaola
ʻO Semaglutide (Rybelsus, Ozempic, NN9535, OG217SC, NNC0113-0217) he glucagon-like peptide 1 (GLP-1) analog lōʻihi, he agonist o GLP-1receptor, me kahi ʻano 2 Therapeutic efficacy o ka maʻi diabetes mellitus (T2DM). ).
Pūnaehana Pono
Ma keʻano laulā, aia ka ʻōnaehana maikaʻi a me ka hōʻoia e uhi ana i nā pae āpau o ka hana ʻana o ka huahana i hoʻopau ʻia.Hana ʻia nā hana hana a me ka hoʻomalu ʻana e like me nā kaʻina hana i ʻae ʻia.Hoʻonohonoho ʻia ka ʻōnaehana hoʻololi a me ka hoʻololi ʻana, a ua mālama ʻia ka loiloi hopena kūpono a me ka noiʻi.Aia nā kaʻina hana kūpono e hōʻoia i ka maikaʻi o ka huahana ma mua o ka hoʻokuʻu ʻana i ka mākeke.
