Inoa | Like gptonycin |
Ka helu helu | 10306060-53-3 |
Mlecular noncula | C72h40N179 |
Kaupaona molebular | 1620.67 |
Nā helu einecs | 600-389-2 |
Malting Point | 202-204 ° C |
Makaʻikua | 2078.2 ± 65.0.0 ° C (wānanaʻia) |
Huakai | 1.45 ± 0.1 G / cm3 (wānana) |
Polout Flall | 87 ℃ |
Nā kūlana mālama | I hoʻopaʻaʻia i loko o ka maloʻo, kūʻai ma FREETER, ma lalo o -20 ° C |
Kū kū | Methanol: slouble5mg / ml |
Acidity chee | (PKA) 4.00 ± 0.10 (wānanaʻia) |
ʻAno | Pauku |
Kāleka | kalaʻoleʻole i ka melemele |
N- [n- (1-oxodecyl)-trp-d-asp-ot-ot-ot ; ecyl) -l-typtophhyl-d-asparagyl-l-oddylglycycycycyl Glutamyl-α, 2-diamino-γ-oxo-benzenebutacid (13-4) lactone; daptomycin
ʻO ka Daptomytic Daptomycinʻo Cyclic Lipopeptide Medibiotika me kahi hoʻolālā hou i laweʻia mai ka bio i ka bionit Ke hoʻololi nei i nā waiwai o ka membrane o ke cytoplasmic e hiki ke hōʻeha i ka hana memberane ma nāʻano he nui a me ka makeʻana i nāʻano nui. Ma kahi o kona hiki ke hana ma ka hapa nui o ka Clinically e pili pono ana i ka Guctinically,ʻo Daptomycin i hōʻikeʻia no ka matroclill, a me ka laina i loaʻa i ka cantoclin, Ua loaʻa iā ia ka hana, a he waiwai nui kēia waiwai i nā maʻi lapaʻau nui no nā maʻi maʻi maʻi maʻi. He maʻi maʻiʻo Eosinophilicʻo Eosinophilic
Loaʻa iā Daptomycin ke hana maikaʻi loa i nā mea bacteriatics maikaʻi loa e kū'ē i nā mea hoʻokūkū antibionitic-resistant, e like me mic = Micud2 ~ 1,6) 0.5 ~ 1μg / ml, a me ka mic o ka citiococcus resistant i ka glycopettictics he 1 ~ 2μg / ml.