Caspofungin no nā maʻi maʻi maʻi
Huahana kikoʻipiop
| Inoa | CORpofringin |
| Ka helu helu | 162808-62-0 |
| Mlecular noncula | C52h88N10o15 |
| Kaupaona molebular | 1093.31 |
| Nā helu einecs | 1806241-263-5 |
| Makaʻikua | 1408.1 ± 65.0 ° C (wānanaʻia) |
| Huakai | 1.36 ± 0.1 G / cm3 (wānana) |
| Acidity chee | (PKA) 9.86 ± 0.26 (wānanaʻia) |
Synonyms
Cs-1171; caspofungine; caspofungin; casporfungin; pneumocandinb0 -1
Kōkua Hōʻa
ʻO Caspofungin ka mea mua echioCandin mua no ka mālamaʻana i nā maʻi o nā ulu lāʻau. I loko o Vitro a me nā hoʻokolohua Vivo e hōʻoia i ka hanaʻo Caspofungin maikaʻi i nā hana antibeacer Hiki i ka caspofungin ke hoʻoponopono i ka pā o ka pākaukau ma ka hoʻopauʻana i ka synthesis o 1,3-β-glucan. ʻO Clinitically, he hopena maikaʻiʻo Capofringin ma ka mālamaʻana i nā mea kūʻai aku o nā mea kūʻai aku a me nā aspergillosis.
Hopena
(1,3) -d -d-Glucan Synthase kahi mea nui o ka pā o ka pā hale o ka pā hale, a hiki i ka caspofungin ke hoʻonāukiuki i kēia enzyme. Ma hope o ka hoʻokeleʻana o ka mea hoʻokele intravenous Ua hoʻonuiʻiaʻo Metabolism o Caspofungin me ka hoʻonuiʻana i ka nui a he dose e pili ana i ka manawa e hoʻomau mau ai i ka moku'āina. No laila, e hoʻokō i nā pae hoʻolālā maikaʻi a pale aku i ka hōʻiliʻiliʻana i ka lāʻau lapaʻau,ʻoi aku ka hana ma mua. I ka hoʻohanaʻana i Cytochrome P4503a4 nā mea komo i ka manawa like, me he mea lā e hoʻonui ai i ka mālama mālamaʻana i ka mālamaʻana o Caspofungone.
Nā hōʻike
ʻO FDA-i noiʻia no ka caspofungin e komo: 1. Wahi a ka'ōlelo aʻoʻana i nā maʻi maʻi maʻi maʻi maʻi (IDSA) . ^. 2. Kāhea iā Candidiasis: Ua'ōleloʻo Idsa i nā echinocandins Hiki iā ia ke hoʻohana e mālama i nāʻano intra-'ōpū o ka'ōpū, peritonitis a me nā maʻi umauma i manaʻoʻia e ka beled. 3 Ua loaʻa kekahi mau haʻawina i loaʻa i ka hopena o ka hanaʻana o ka terapetitic o ka caspofungin e hoʻohālikelikeʻia i kēlāʻano o ka flucazole. 4. Uaʻaeʻiaʻo Goperkisis: Uaʻaeʻiaʻo Caspofungin no ka mālamaʻana i nā maʻi antifurilly Eia naʻe,ʻaʻole i'ōleloʻiaʻo Echinocandin e like me keʻano o ka hana mua.
