Hoʻohana ʻia ʻo RU-58841 e like me ka pale ʻana i ka lauoho a me ke ʻano ʻōhule kāne
Huahana Huahana
| inoa | RU-58841 |
| Helu CAS | 154992-24-2 |
| ʻAno molekala | C17H18F3N3O3 |
| Kaumaha molekula | 369.34 |
| Helu EINECS | 1592732-453-0 |
| Lae paila | 493.6±55.0 °C(Wānana ʻia) |
| ʻO ka mānoanoa | 1.39 |
| Kūlana mālama | Hoʻopaʻa ʻia i kahi maloʻo, E mālama i loko o ka paʻukū, ma lalo o -20 ° C |
| Puka | Pauda |
| kalakala | Keʻokeʻo |
| Hoʻopili | ʻeke PE + ʻeke Aluminum |
Nā huaʻōlelo like
RU58841;4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl-methyl onitrile;4-[3-(4-Hydroxybutyl)-4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2-(trifluoroMethyl)ben zonitrile;RU-58841E:candyli(at)speedgainpharma(dot)com;CS-637;RU588841;RU58841;RU58841;RU-58841
Ka hopena lāʻau lapaʻau
wehewehe
ʻO RU 58841 (PSK-3841) kahi mea hoʻopale hoʻokipa androgen e hoʻoikaika i ka ulu hou o ka lauoho.ʻO RU58841 kahi lāʻau noiʻi i hana ʻia no ka mālama ʻana i ka androgenic alopecia, i ʻike ʻia ʻo ka male pattern baldness (MPD).
Ma ke ʻano he anti-androgen topical, ʻaʻole like kāna kumu o ka hana me ka finasteride. Hana pololei ʻo Finasteride i ka 5α reductase, ke kāohi i ka hoʻololi ʻana o ka testosterone i DHT, a hoʻemi i ka ʻike o DHT i ke kino. Hoʻopili ʻo RU58841 i ka pilina ma waena o ka dihydrotestosterone a me ka lauoho follicle receptors, ʻaʻole ia e hōʻemi pololei i ka ʻike DHT, akā hoʻemi ia i ka paʻa ʻana o ka DHT a me ka lauoho follicle receptors, i mea e hoʻokō ai i ke kumu o ka mālama ʻana i ka androgenetic alopecia.
4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau ʻO ka synthesis intermediates.Ina 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile i inhaled, E hoʻoneʻe i ka mea maʻi i ka ea hou;Inā pili ka ʻili, e wehe i nā lole i haumia, e holoi pono i ka ʻili me ke kopa a me ka wai, a e ʻimi i ka lāʻau lapaʻau inā loaʻa ka pilikia;
Ka hopena ʻaoʻao
Hoʻohana ʻia ʻo RU58841 i ke poʻo, hoʻopili ʻia e nā follicles lauoho, a me ka manaʻo, hiki ke komo i ke kahe koko a pili i nā ʻāpana ʻē aʻe o ke kino. Akā ʻaʻole i loaʻa nā hopena ʻaoʻao systemic i nā haʻawina o ka noi topical i nā monkey. Eia naʻe, ʻōlelo kekahi poʻe i hoʻāʻo iā RU58841 ua loaʻa iā lākou kekahi mau hopena ʻaoʻao mai ka hoʻohana ʻana i ka RU, e like me ka ʻili o ka ʻili, ka emi ʻana o ka libido, ka erectile dysfunction, nausea, nā maka ʻulaʻula, dizziness, a me ke poʻo.
