Pegcetacoplan

API Pegcetacoplan

ʻO Pegcetacoplan kahi peptide cyclic pegylated e hana ana ma ke ʻano he C3 complement inhibitor, i hoʻomohala ʻia no ka mālama ʻana i nā maʻi complement-mediated e like me ka paroxysmal nocturnal hemoglobinuria (PNH) a me ka geographic atrophy (GA) i ka macular degeneration pili makahiki.

Mechanism & Research:
Hoʻopili ʻo Pegcetacoplan e hoʻopiha i ka protein C3 a me C3b, e pale ana i ka hoʻāla ʻana o ka cascade complement. Hoemi keia:
Hemolysis a me ka mumū ma PNH
ʻO ka pōʻino o ke kino retina i ka atrophy ʻāina
ʻO ka ʻeha kino i hoʻopaʻa ʻia i loko o nā maʻi ʻē aʻe