Motixafortide

Motixafortide API

ʻO Motixafortide kahi peptide antagonist synthetic CXCR4 i hoʻomohala ʻia e hoʻoneʻe i nā cell hematopoietic stem (HSCs) no ka hoʻololi autologous a ke aʻo ʻia nei hoʻi i ka oncology a me ka immunotherapy.

Mechanism & Research:

Hoʻopaʻa ʻo Motixafortide i ka axis CXCR4–SDF-1, e alakaʻi ana i:
ʻO ka hoʻoneʻe wikiwiki ʻana o nā pūnaʻi kumu i loko o ke koko peripheral
Hoʻonui ʻia ka hoʻopiʻi ʻana i nā cell immune a me ka infiltration tumor
ʻO ka synergy hiki ke hoʻopaʻa ʻia me ka checkpoint inhibitors a me ka chemotherapy

Ua hōʻike ʻo ia i ka hoʻoulu ʻana o ka stem cell i hoʻohālikelike ʻia me nā mobilizers i loaʻa i nā hoʻokolohua lapaʻau.
Nā hiʻohiʻona API (Gentolex Group):

ʻO ka peptide synthetic maʻemaʻe kiʻekiʻe
Nā kūlana hana like GMP
He kūpono no nā ʻano hana injectable

Kākoʻo ʻo Motixafortide API i ka noiʻi kiʻekiʻe i ka lāʻau stem cell a me ka maʻi immunotherapy.