Glucagon

Glucagon API

ʻO Glucagon kahi hormone peptide kūlohelohe i hoʻohana ʻia ma ke ʻano he lāʻau ulia pōpilikia no ka hypoglycemia koʻikoʻi a aʻo ʻia no kāna kuleana i ka hoʻoponopono metabolic, pohō kaumaha, a me nā diagnostics digestive.

Mechanism & Research:

Hoʻopili ʻo Glucagon i ka glucagon receptor (GCGR) i loko o ke ake, e hoʻoulu ai:

ʻO ka haʻihaʻi glycogen e hoʻonui i ka glucose koko

ʻO ka lipolysis a me ka hoʻoulu ʻana i ka ikehu

ʻO ka hoʻololi ʻana i ka motility gastrointestinal (hoʻohana ʻia i ka radiology)

Ke ʻimi ʻia nei hoʻi i ka momona, ka maʻi diabetes type 2, a me nā lāʻau lapaʻau ʻelua/triple agonist me GLP-1 a me GIP.

Nā hiʻohiʻona API (Gentolex Group):

Peptide maʻemaʻe kiʻekiʻe (≥99%)

Hana ʻia ma o ka solid-phase peptide synthesis (SPPS)

ʻO ka maikaʻi like GMP

He kūpono no nā injectable a me nā pahu pilikia

Pono ʻo Glucagon API no ka hoʻopakele ʻana i ka hypoglycemia, ke kiʻi diagnostic, a me ka noiʻi maʻi metabolic.