Fmoc-Ile-Aib-OH

Fmoc-Ile-Aib-OH

ʻO Fmoc-Ile-Aib-OH kahi poloka hale dipeptide i hoʻohana ʻia i ka solid-phase peptide synthesis (SPPS). Hoʻohui ia i ka isoleucine pale ʻia Fmoc me Aib (α-aminoisobutyric acid), kahi amino acid non-natural e hoʻonui ai i ka paʻa helix a me ka pale protease.

 
Noiʻi a me nā noi:

Kūpono no ka hoʻolālā ʻana i nā peptides paʻa, helical

Hoʻohana ʻia i ka hoʻomohala peptidomimetic a me ka hoʻolālā lāʻau

Hoʻomaikaʻi i ka conformational rigidity a me ka metabolic stability

Nā hiʻohiʻona huahana (Gentolex Group):

Maʻemaʻe kiʻekiʻe ≥99%

Mālama ʻia ʻo Fmoc, SPPS-kūpono

ʻO Fmoc-Ile-Aib-OH kahi mea hana waiwai no ka peptide kiʻekiʻe a me ka noiʻi therapeutic.