Elamipretide

API Elamipretide

ʻO ka Elamipretide kahi tetrapeptide i manaʻo ʻia i ka mitochondria i hoʻomohala ʻia e mālama i nā maʻi i hoʻokumu ʻia e ka mitochondrial dysfunction, me ka myopathy mitochondrial mua, Barth syndrome, a me ka pau ʻole o ka naʻau.

Mechanism & Research:
Hoʻopili ʻo Elamipretide i ka cardiolipin i loko o ka membrane mitochondrial i loko, e hoʻomaikaʻi ana:
ʻO ka bioenergetics mitochondrial
Hana ʻia ʻo ATP
ʻO ka hanu kelepona a me ka hana o ke kino

Ua hōʻike ʻo ia i ka hiki ke hoʻihoʻi i ke ʻano mitochondrial, hōʻemi i ke koʻikoʻi oxidative, a hoʻomaikaʻi i ka hana ʻana o ka ʻiʻo a me ka naʻau i nā haʻawina ʻelua a me nā haʻawina preclinical.