BPC-157

API BPC-157

ʻO BPC-157 (inoa piha: Body Protection Compound 157) he peptide pōkole synthetic i haku ʻia me 15 amino acids, i loaʻa mai kahi ʻano o nā protein pale kūlohelohe i ka wai ʻōpū o ke kanaka. Ua hōʻike ʻo ia i ka hoʻoponopono ʻana i ka ʻiʻo nui a me nā hiki anti-inflammatory i nā haʻawina hoʻokolohua a ua manaʻo nui ʻia ʻo ia he moho lāʻau lapaʻau multifunctional multifunctional.

Ma ke ʻano he lāʻau lapaʻau ikaika (API), ua hoʻohana ʻia ʻo BPC-157 i nā kahua noiʻi ʻepekema a puni ka honua e ʻimi i kāna hana olaola ma ka ʻōpū o ka ʻōpū, musculoskeletal system, nerve system, cardiovascular system and soft tissue repair, ʻoi loa i ka hoʻoponopono trauma a me ka noiʻi anti-inflammatory.

ʻO ka noiʻi a me ka hana pharmacological o ka hana

Ua aʻo nui ʻia ka BPC-157, ʻoi aku hoʻi i loko o nā hoʻokolohua holoholona in vivo a me nā hiʻohiʻona in vitro cell, a ua ʻike ʻia aia nā hopena pharmacological kumu:

1. Hoʻoponopono hou a me ka hoʻoponopono ʻeha

Hoʻoikaika i ka tendon, ligament, iwi a me nā ʻiʻo palupalu, a hiki ke hoʻonui i ka angiogenesis (angiogenesis).

E hoʻolalelale i ka ho'ōla ʻana i ka ʻeha, ka hoʻoponopono ʻana ma hope o ka hana ʻana a me ka hoʻihoʻi ʻana i nā ʻeha ʻili palupalu, i hōʻoia ʻia i nā ʻano holoholona e like me ka haki ʻana o ka tendon, ka ʻiʻo ʻiʻo, a me ka haki.

2. Ka pale ʻana a me ka hoʻoponopono ʻana

I nā hiʻohiʻona e like me ka maʻi ʻōpū o ka ʻōpū, enteritis, a me ka colitis, loaʻa ka BPC-157 i kahi hopena pale mucosal nui.

Hiki iā ia ke pale i ka pōʻino o ka ʻōpū i hana ʻia e nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) a hoʻoikaika i ka ho'ōla ʻana o ka mucosal intestinal.

3. Anti-inflammatory a me ka immunomodulatory

Hoʻoponopono ia i ke koena o ka ʻōnaehana pale ma ke kāohi ʻana i nā mea pro-inflammatory (e like me TNF-α, IL-6) a me ka hoʻonui ʻana i nā mea anti-inflammatory.

Loaʻa iā ia ka waiwai kūpono ma ke ʻano he lapaʻau kōkua no nā maʻi ʻeha mau e like me **rheumatoid arthritis a me ka maʻi ʻāʻī o ka ʻōpū (IBD)**.

4. Neuroprotection a me ka neuroregeneration

I nā hiʻohiʻona ma hope o ka hōʻeha ʻana o ke kuamoʻo, ka hoʻopaʻa ʻana o ke aʻalolo, a me nā hanana cerebrovascular, hiki i ka BPC-157 ke hoʻoikaika i ka hoʻoulu hou ʻana o ke aʻalolo a hoʻemi i ka pōʻino nerve.

Hiki iā ia ke hakakā i nā pilikia ma ke kahua neuropsychiatric e like me ka hopohopo, ke kaumaha, a me ka hilinaʻi ʻana i ka waiʻona (pae hoʻokolohua).

5. Ka mālama ʻana i ka maʻi cardiovascular a me ka vascular

Hiki i ka BPC-157 ke hoʻomaikaʻi i ka vascular permeability a hoʻoikaika i ka hoʻoponopono microvascular, a ua manaʻo ʻia he hopena maikaʻi ia i nā maʻi e like me ka myocardial ischemia, venous thrombosis, a me ka ʻeha arterial.

Nā hualoaʻa noiʻi hoʻokolohua a preclinical

ʻOiai ʻaʻole i ʻae nui ʻia ka BPC-157 no nā lāʻau lapaʻau kanaka, ua hōʻike ʻia ma nā hoʻokolohua holoholona:

ʻO ka wikiwiki nui o ka manawa hoʻoponopono kiko (e like me 50% ka wikiwiki o ka ho'ōla ʻana o ka tendon)

E hoʻemi nui i ka maʻi o ke kahe ʻana o ka ʻōpū, ka ʻeha o ka ʻōpū, a me ka ʻeha colon

E hoʻomaikaʻi i ka hoʻihoʻi ʻana o ka nerve conduction a hoʻonui i ka hana o ka wahi innervated

Hoʻonui i ka angiogenesis a me ka nui o ka hoʻokumu ʻana o ka ʻiʻo granulation

Ma muli o kēia mau hopena, ke lilo nei ʻo BPC-157 i mole mole noiʻi koʻikoʻi ma nā kahua o ka hoʻoponopono hou ʻana ma hope o ka traumatic, nā ʻeha haʻuki, nā maʻi ʻōpū, a me nā maʻi neurodegenerative.
ʻO ka hana API a me ka mana maikaʻi

ʻO ka BPC-157 API i hāʻawi ʻia e kā mākou Gentolex Group e lawe i ka hana solid phase synthesis (SPPS) a hana ʻia ma lalo o nā kūlana GMP. Loaʻa iā ia nā ʻano penei:

Maʻemaʻe kiʻekiʻe: ≥99% (ʻike HPLC)

Ke koena haumia haʻahaʻa, ʻaʻohe endotoxin, ʻaʻohe haumia metala kaumaha

Paʻa paʻa, hoʻihoʻi ikaika, kākoʻo i ka hoʻohana pae injection

E kākoʻo i ka lako o ka pae gram a me kilokani e hoʻokō i nā pono o nā pae like ʻole mai R&D a hiki i ka ʻoihana.