Melanotana II

Melanotan II API

Melanotana IIhe synthetic cyclic heptapeptide analog oα-melanocyte-stimulating hormone (α-MSH), hoʻomohala ihoʻoulu i ka melanogenesis, hoʻonuiPale UV, a modulatenā hana pili i ka wahine a me ka metabolic. He hana ia ma ke ano heagonist koho ʻoleo nā melanocortin receptors, ʻoi akuMC1R, MC3R, aMC4R.

Ua aʻo mua ʻia no kānaʻili ʻiliapale kiʻinā waiwai, ua hōʻike pū ʻo Melanotan II i nā hopena mahoʻonui libido, hoʻopau ʻai, akoena ikehu, e hana ana i ka peptide noiʻi multifunctional me ka hoihoi i ka dermatology, endocrinology, a me ka lāʻau lapaʻau.

Mechanism of Action

Hana ʻia ʻo Melanotan II ma ka hoʻāla ʻana i kekahi mau melanocortin receptors:

• MC1R: Hooikaikahana melanin→ hoʻonui i ka pigmentation ʻili a me ka pale UV

• MC3R / MC4R: Komo i lokohoʻomalu ʻai, hoʻonui libido, ahomeostasis ikehu

• Kaʻa i ka pale koko-lolo, e hoʻopili ana i nā ala neurohormonal waena

Noiʻi a me nā noi kūpono

ʻOiai ʻaʻole i ʻae ʻia no ka hoʻohana olakino, ua aʻo nui ʻia ʻo Melanotan II no kēia mau mea:

1. ʻIli Pigmentation & Paleʻa UV

• Hoʻolahaeumelanin synthesis, alakai ana iʻili maoli

• Hāʻawinā hopena pale kiʻime ka ʻole o ka lā

• Loaʻa no ka hōʻemi ʻana i ka maʻi kanesa ʻili i nā poʻe ʻili maikaʻi

2. Hoʻopilikia i ke kino

• Hōʻike ʻia iāe hoʻonui i ka libido a me ka hoʻoulu wahinema na kane a me na wahine

• Ua aʻo ʻia ma ke ʻano he lāʻau lapaʻau nohoʻopau i ka erectile (ED)ma o ka ho'ā 'ana o MC4R

3. Ka 'ai a me ke kaumaha

• Meihoemi i ka makemake a me ka aima ka hana ʻana ma nā ala hypothalamic

• Hiki ke hoʻohui i lokonoiʻi obesity

Nā hiʻohiʻona API (na Gentolex Group)

• Maʻemaʻe kiʻekiʻe ≥ 99%(HPLC & LC-MS hōʻoia ʻia)

• Hana ʻia ma oka hana peptide synthesis (SPPS)

• Haʻahaʻa endotoxin, haʻahaʻa koena solvents

• Loaʻa maR&D i ka pālākiō pāʻoihana