Fmoc-Lys(Pal-Glu-OtBu)-OH

Fmoc-Lys(Pal-Glu-OtBu)-OH

ʻO Fmoc-Lys (Pal-Glu-OtBu) -OH kahi papa hale kūkulu hale lipidated amino acid i hoʻolālā ʻia no ka conjugation peptide-lipid. Hōʻike ia i ka lysine pale ʻia ʻo Fmoc me kahi kaulahao ʻaoʻao palmitoyl-glutamate, hoʻonui i ka pili o ka membrane a me ka bioavailability.

 
Noiʻi a me nā noi:

Hoʻohana ʻia i ka lipopeptide synthesis a me ka hoʻolālā kano

Hoʻonui i ka paʻa o ka peptide, ka lawe ʻana i nā cell, a me ka lipophilicity

He waiwai i ka lawe ʻana i ka lāʻau lapaʻau a me nā peptides immune-modulating

Nā hiʻohiʻona huahana (Gentolex Group):

Maʻemaʻe kiʻekiʻe ≥99%, SPPS-kūpono

Nā hui pale: Fmoc, OtBu
He kūpono ʻo Fmoc-Lys (Pal-Glu-OtBu) -OH no ka hoʻomohala ʻana i nā therapeutics peptide lipidated a me nā ʻōnaehana lawe.