Fmoc-Gly-Gly-OH

Fmoc-Gly-Gly-OH

Noi noiʻi:
ʻO Fmoc-Gly-Gly-OH kahi dipeptide i hoʻohana ʻia ma ke ʻano he papa kūkulu hale ma ka solid-phase peptide synthesis (SPPS). Loaʻa iā ia nā koena glycine ʻelua a me kahi Fmoc-protected N-terminus, e ʻae ana i ka elongation chain peptide controlled. Ma muli o ka liʻiliʻi a me ka maʻalahi o ka glycine, ua aʻo pinepine ʻia kēia dipeptide i ka pōʻaiapili o ka peptide backbone dynamics, linker design, a me ka hoʻohālikelike ʻana i nā peptides a me nā protein.

Hana:
Hāʻawi ʻo Fmoc-Gly-Gly-OH i kahi ʻāpana maʻalahi a me ka uku ʻole i loko o kahi kaʻina peptide. Hoʻokomo nā koena Glycine i ke kūʻokoʻa conformational, e hoʻolilo i kēia dipeptide i mea kūpono no nā loulou, huli, a i ʻole nā ​​wahi i kūkulu ʻole ʻia i nā peptides hana. Hoʻohana nui ʻia ia i ka hoʻolālā ʻana o nā peptides bioactive, substrates enzyme, a me nā bioconjugates kahi i makemake ʻia ai ka liʻiliʻi steric hindrance a me ka maʻalahi.